- Clb5 Clb6 Mutants
- clb5∆ clb6∆
- TAB6-1 clb5∆ clb6∆
- cdc20∆ clb5∆
- cdc20∆ pds1∆ clb5∆
- CLB2-db∆ clb5∆
- CLB2-db∆ clb5∆ in galactose
- cln1∆ cln2∆ clb5∆ clb6∆
- CLB5-db∆
- CLB5-db∆ sic1∆
- CLB5-db∆ pds1∆
- CLB5-db∆ pds1∆ cdc20∆
- GAL-CLB5
- GAL-CLB5 cdh1∆
- GAL-CLB5 sic1∆
- GAL-CLB5-db∆
- cln1∆ cln2∆ cln3∆ multi-copy CLB5
- cln1∆ cln2∆ cln3∆ GAL-CLB5
CLB5-db∆ pds1∆ cdc20∆
debug: ,
test user =
test db =
Simulation:
Change of parameters: kdb5"=0, ks1pds"=ks2pds"=0,
ks20'=ks20"=0.
Length of G1 phase: 34.5 min.
Arrest: Telophase arrest.
Experiments:
Wasch, R. and Cross, F. (2002). APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit. Nature 418:556-562.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Fig. 1, telophase arrest.
Comments: This shows that Cdc20 has other essential targets beside Clb5 and Pds1, namely Clb2.